Early Diagnosis for Ovarian Cancer

Collaborated with Harvard Medical School neonanotech Collaborated with Harvard Medical School


Introduction

  • Non-invasive in-vitro diagnostic method using exosome biomarker secreted from ovarian cancer cells
  • Ovarian cancer is one of the most difficult to diagnose early due to the absence of specific observable symptoms.
  • The survival rate is only 10 to 20% if detected at 3rd~4th stages, but the 5 year survival rate is 92% if detected early.
  • Lab testing method for early diagnosis of ovarian cancer by Harvard Medical School has been realized on the lab-on-a-chip.
  • Ovarian cancer cell-derived exosomes are reacted to antibody and enzyme in the LOAC chamber, and the cancer is detected by amplified electrochemical signals.
Early Diagnostics for Ovarian Cancer
neonanotech Early Diagnostics for Ovarian Cancer

Specifications

  • Just 10 uL sample can check the test results within one hour.
  • A substrate solution and an amplified circuit are used to efficiently detect the electrochemical signal, and to improve its sensitivity.
  • Signal amplification over the second time enhances the detection capacity 103 better than ELISA (Enzyme Linked Immunosorbent assay).

Development on going